Beyond the software, the 2021 client demands specific hardware for its new "science," such as CPUs with AVX instructions for Python dependencies and certified NVIDIA Quadro or RTX cards for CUDA-based acceleration.
BIOVIA’s support portal (case-sensitive login) offers the DS2021_Client_Installation_Guide.pdf , which covers edge cases like cluster installs and multi-license-server failover. discovery studio 2021 client install