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If you are analyzing sequence data, PROSITE (hosted by the Swiss Institute of Bioinformatics) remains a gold standard tool for annotation.

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This is the biggest risk. If you build a site on Prosites, you cannot easily pick it up and move it to another host (like GoDaddy or Bluehost). If you ever decide to leave Prosites, you essentially have to rebuild your site from scratch on a new platform. If you are analyzing sequence data, PROSITE (hosted

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